Artichoke leaf
Cynara cardunculus L.Asteraceae // leaf
Overview
Plant parts
leaf
Known constituents
cynarin, chlorogenic acid, sesquiterpene lactones
Research corpus coverage
Chemistry notes
- CHEMISTRY: Relevant reported constituents include cynarin; chlorogenic acid; sesquiterpene lactones; constituent presence alone does not establish clinical efficacy.
Uses & Evidence
Traditional / historical use
Documented traditional use — not a claim of established efficacy.
TRADITIONAL: Artichoke leaf has been used for dyspepsia; bile flow; lipid support; this records historical/traditional use and does not establish efficacy.
MODERATE · regulatory monograph · WHO Monographs on Selected Medicinal Plants
Modern evidence
EVIDENCE: For the major use set (dyspepsia; bile flow; lipid support), the evidence assessment is limited/mixed: Moderate evidence for functional dyspepsia; limited/mixed for cholesterol.
MODERATE · regulatory monograph and mixed scientific literature · WHO Monographs on Selected Medicinal Plants
Mixed findings, product heterogeneity, or indirect evidence are preserved in the detailed profile.
Preparation
Forms used traditionally
A listed form does not imply it suits every plant part, or that one preparation is interchangeable with another — see the plant’s own notes below.
PREPARATION: The medicinal material is leaf; traditional and modern forms include infusion/tea, tincture, powder/capsule, extract. No dose or potency is specified.
MODERATE · regulatory monograph · EMA European Union herbal monographs and list entries
Preparation-specific evidence should not be generalized across extracts, teas, oils, or whole herb.
Safety
Additional safety notes (general, unstructured)
Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.
SAFETY: Major issues include GI upset; Asteraceae allergy. Contraindications/cautions include Biliary obstruction; Asteraceae allergy.
MODERATE · regulatory monograph · EMA European Union herbal monographs and list entries
SAFETY: Clinically relevant interaction concerns include Potential additive lipid-lowering and bile-related effects.
MODERATE · regulatory monograph · EMA European Union herbal monographs and list entries
Some interactions are theoretical or based on case reports/pharmacokinetics rather than outcome trials.
SAFETY: Pregnancy/lactation reference: Insufficient pregnancy/lactation evidence.
MODERATE · regulatory monograph or evidence synthesis · WHO Monographs on Selected Medicinal Plants
Absence of evidence is not evidence of safety.
Preparation × species risk matrix
Unknown means insufficient evidence was located — not that a form is safe.
Cats
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Dogs
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Identity
Botanical synonym
Cynara scolymus L. is often treated as a cultivar group
Taxonomic identity note
- Artichoke leaf is treated here as Cynara cardunculus L. in the family Asteraceae; recorded older names include Cynara scolymus L. is often treated as a cultivar group.
Sources
Research records are source-linked but may not yet be editorially reviewed.
WHO monograph
EMA monograph
- Plants of the World Online1 claim
botanical taxonomy database