Echinacea
Echinacea purpurea (L.) MoenchAsteraceae // aerial parts · root
Overview
Plant parts
aerial parts, root
Known constituents
alkamides, caffeic-acid derivatives, polysaccharides
Research corpus coverage
Chemistry notes
- CHEMISTRY: Relevant reported constituents include alkamides; caffeic-acid derivatives; polysaccharides; constituent presence alone does not establish clinical efficacy.
Uses & Evidence
Traditional / historical use
Documented traditional use — not a claim of established efficacy.
TRADITIONAL: Echinacea has been used for colds; respiratory infections; wound care; this records historical/traditional use and does not establish efficacy.
MODERATE · evidence synthesis/fact sheet · NCCIH Herbs at a Glance
Modern evidence
EVIDENCE: For the major use set (colds; respiratory infections; wound care), the evidence assessment is limited/mixed: Limited/mixed systematic reviews and trials for preventing or shortening colds; preparation heterogeneity is substantial.
MODERATE · systematic review/meta-analysis · Cochrane: Echinacea for preventing and treating the common cold
Mixed findings, product heterogeneity, or indirect evidence are preserved in the detailed profile.
Preparation
Forms used traditionally
A listed form does not imply it suits every plant part, or that one preparation is interchangeable with another — see the plant’s own notes below.
PREPARATION: The medicinal material is aerial parts; root; traditional and modern forms include decoction, tincture, powder/capsule, standardized extract, infusion/tea, extract. No dose or potency is specified.
MODERATE · regulatory monograph · EMA European Union herbal monographs and list entries
Preparation-specific evidence should not be generalized across extracts, teas, oils, or whole herb.
Safety
Additional safety notes (general, unstructured)
Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.
SAFETY: Major issues include Allergy, especially Asteraceae; GI upset; rare liver injury reports. Contraindications/cautions include Asteraceae allergy; caution with autoimmune disease.
HIGH · observational/case series and expert review · LiverTox: Herbal and Dietary Supplements
SAFETY: Clinically relevant interaction concerns include Theoretical antagonism of immunosuppressants; CYP effects uncertain.
MODERATE · observational/case series and expert review · LiverTox: Herbal and Dietary Supplements
Some interactions are theoretical or based on case reports/pharmacokinetics rather than outcome trials.
SAFETY: Pregnancy/lactation reference: Pregnancy data are limited but observational data have not shown a clear major signal.
MODERATE · regulatory monograph or evidence synthesis · NCCIH Herbs at a Glance
Absence of evidence is not evidence of safety.
Preparation × species risk matrix
Unknown means insufficient evidence was located — not that a form is safe.
Cats
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Dogs
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Identity
- Related, not interchangeableNarrow-leaved echinacea
Echinacea products may use E. purpurea, E. angustifolia, or mixtures.
MODERATE · GBIF taxonomic backbone and Apothecary corpus identity note
- Related, not interchangeablePale purple coneflower
Echinacea products may use E. purpurea, E. pallida, or mixtures.
MODERATE · GBIF taxonomic backbone and Apothecary corpus identity note
- Synonym
GBIF resolves Rudbeckia purpurea L. as a synonym of Echinacea purpurea. The older name still appears in herbal and taxonomic literature.
HIGH · GBIF Species Match API
Botanical synonym
Rudbeckia purpurea L.
Taxonomic identity note
- Echinacea is treated here as Echinacea purpurea (L.) Moench in the family Asteraceae; recorded older names include Rudbeckia purpurea L..
Sources
Research records are source-linked but may not yet be editorially reviewed.
- NCCIH Herbs at a Glance2 claims
NCCIH fact sheet
NIH LiverTox monograph
authoritative taxonomic database plus curated corpus note
- Plants of the World Online1 claim
botanical taxonomy database
EMA monograph
systematic review
WHO monograph
- GBIF Species Match API1 claim
authoritative taxonomic database