San Pedro cactus
Echinopsis pachanoiCactaceae // stems
Also known as: Trichocereus pachanoi, wachuma, huachuma
Preparation
Overview
Plant parts
stems
Known constituents
mescaline, minor phenethylamines
Research corpus coverage
Chemistry notes
- Principal reported constituents include mescaline, minor phenethylamines; broad class: serotonergic psychedelic phenethylamine.
Uses & Evidence
Traditional / historical use
Documented traditional use — not a claim of established efficacy.
No traditional-use records in this corpus.
Modern evidence
Taxonomy within Echinopsis/Trichocereus is unsettled; E. peruviana and hybrids are often conflated.
MODERATE · Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging
Identity/attribution caution.
Safety
Human
- High risk
Safety severity is HIGH: prolonged psychological and autonomic effects; nausea; accident risk
Intrinsic toxicity · HIGH · Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging
Additional safety notes (general, unstructured)
Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.
Safety severity is HIGH: prolonged psychological and autonomic effects; nausea; accident risk
HIGH · Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging
Preparation × species risk matrix
Unknown means insufficient evidence was located — not that a form is safe.
Cats
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Dogs
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Identity
- Synonym
GBIF lists Cereus pachanoi (Britton & Rose) Werderm. as a taxonomic synonym of Trichocereus macrogonus.
HIGH · GBIF Species Synonyms API
- Former name
GBIF treats the corpus name Echinopsis pachanoi (Britton & Rose) H.Friedrich & G.D.Rowley as a synonym and points to Trichocereus macrogonus as the accepted usage.
MODERATE · GBIF Species Match API
Common name
Trichocereus pachanoi, wachuma, huachuma
Traditions
Andean curanderismo and archaeological ceremonial contexts
Peru and Ecuador // pre-Columbian iconography/archaeology and living practice // living tradition with historical evidence
Ethnobotanical
San Pedro cactus is documented in Andean curanderismo and archaeological ceremonial contexts in Peru and Ecuador for healing, divination and night ceremony.
MODERATE · Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging
Ritual
Documented functions include healing, divinatory, visionary; these functions are tradition-specific and should not be generalized across cultures.
MODERATE · Natural or artificial: An example of topographic spatial distribution analysis of mescaline in cactus plants by matrix-assisted laser desorption/ionization mass spectrometry imaging
Legal
Legal status changes over time and by jurisdiction — this is a dated snapshot, not current law.
International · Checked 2026-08-09
Varies substantially by country; constituent controls and plant-specific controls are not uniform.
State / municipal · Checked 2026-08-09
Material state and municipal variation may apply; verify jurisdiction at time of use.
US Federal · Checked 2026-08-09
Cactus itself is generally not named federally, but mescaline is Schedule I; intended preparations may create legal exposure.
Sources
Research records are source-linked but may not yet be editorially reviewed.
peer-reviewed article
- 21 CFR 1308.11 — Schedule I1 claim
government/regulatory source
- GBIF Species Synonyms API1 claim
authoritative taxonomic database
- GBIF Species Match API1 claim
authoritative taxonomic database