Mapacho / strong tobacco

Research corpus coverage

Chemistry notes

• Principal reported constituents include nicotine, nornicotine; broad class: nicotinic acetylcholine receptor agonists.

Traditional / historical use

Documented traditional use — not a claim of established efficacy.

No traditional-use records in this corpus.

Modern evidence

• Often confused with N. tabacum; nicotine content can be much higher and preparations vary.

  MODERATE · “Tobacco Is the Chief Medicinal Plant in My Work”: Therapeutic Uses of Tobacco in Peruvian Amazonian Medicine Exemplified by the Work of a Maestro Tabaquero

  Identity/attribution caution.

Human

• Critical

  Safety severity is CRITICAL: acute nicotine poisoning can cause vomiting, hypertension, seizures, respiratory failure and death; dependence risk

  Intrinsic toxicity · HIGH · “Tobacco Is the Chief Medicinal Plant in My Work”: Therapeutic Uses of Tobacco in Peruvian Amazonian Medicine Exemplified by the Work of a Maestro Tabaquero

Cats

• High risk

  The page’s general toxicity-to-pets text describes tobacco (Nicotiana) poisoning as causing initial low heart and respiratory rates, followed by overstimulation, uncontrolled urination or defecation, tremors, seizures, paralysis, and death; it does not separately assign a toxicity designation to cats.

  Intrinsic toxicity · UNKNOWN · Tobacco and related nicotine-containing products; no preparation-specific distinction provided · MODERATE · poison_control_database · Tobacco Is Toxic To Dogs | Pet Poison Helpline®

• Caution

  Nicotine ingestion may cause acute toxicosis in cats, but the page states that no established toxic threshold exists for cats.

  Intrinsic toxicity · OTHER · nicotine or nicotine-containing tobacco products · HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

• Caution

  Environmental tobacco smoke exposure was associated with increased risk of malignant lymphoma in pet cats.

  Route-specific · INHALATION · Environmental tobacco smoke · MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

Dogs

• High risk

  Nicotine ingestion can cause clinically important acute toxicosis in dogs; the page states that a dose of 9–12 mg/kg is considered lethal.

  Intrinsic toxicity · OTHER · nicotine or nicotine-containing tobacco products · HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

• High risk

  A dog died from nicotine poisoning after eating an electronic cigarette capsule.

  Intrinsic toxicity · OTHER · Electronic cigarette capsule · HIGH · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

• High risk

  Nicotine ingestion is dangerous in dogs.

  Intrinsic toxicity · OTHER · Nicotine-containing tobacco product; specific preparation not stated · HIGH · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

• High risk

  The page states that tobacco (Nicotiana) is toxic to dogs. Nicotine and other pyridine and piperidine alkaloids may cause initial bradycardia and respiratory depression, followed by overstimulation, uncontrolled urination or defecation, tremors, seizures, paralysis, and death.

  Intrinsic toxicity · UNKNOWN · Tobacco and related nicotine-containing products; no preparation-specific distinction provided · HIGH · poison_control_database · Tobacco Is Toxic To Dogs | Pet Poison Helpline®

• Caution

  Exposure to environmental tobacco smoke was associated with cancer of the nasal cavity and paranasal sinuses in pet dogs.

  Route-specific · INHALATION · Environmental tobacco smoke · MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

• Caution

  Passive exposure to environmental cigarette smoke was associated with airway limitation in dogs with chronic cough.

  Route-specific · INHALATION · Environmental cigarette smoke · MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

Cats & dogs

• High risk

  Ingestion of tobacco-derived nicotine in e-liquid or other nicotine-containing products can cause rapid, potentially severe nicotine poisoning in companion animals; severe cases may result in coma, cyanosis, or death.

  Intrinsic toxicity · OTHER · E-liquid, pre-filled cartridges, bulk refill bottles, cigarettes, cigars, nicotine patches, or nicotine gum · MODERATE · veterinary_hospital_guidance · E-cigarettes and Pet Safety | VCA Animal Hospitals

• High risk

  Ingestion of nicotine-containing tobacco products, including chewing tobacco, cigarettes, cigars, bidis, nicotine-replacement products, and cigarette butts, may be toxic to cats and dogs.

  Intrinsic toxicity · OTHER · tobacco products and nicotine preparations · HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

Additional safety notes (general, unstructured)

Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.

• Safety severity is CRITICAL: acute nicotine poisoning can cause vomiting, hypertension, seizures, respiratory failure and death; dependence risk

  HIGH · “Tobacco Is the Chief Medicinal Plant in My Work”: Therapeutic Uses of Tobacco in Peruvian Amazonian Medicine Exemplified by the Work of a Maestro Tabaquero

• Ingestion of tobacco-derived nicotine in e-liquid or other nicotine-containing products can cause rapid, potentially severe nicotine poisoning in companion animals; severe cases may result in coma, cyanosis, or death.

  MODERATE · veterinary_hospital_guidance · E-cigarettes and Pet Safety | VCA Animal Hospitals

  The page refers to tobacco-derived nicotine but does not identify the botanical tobacco species; applicability to Nicotiana rustica is therefore not species-specific.

• Ingestion of nicotine-containing tobacco products, including chewing tobacco, cigarettes, cigars, bidis, nicotine-replacement products, and cigarette butts, may be toxic to cats and dogs.

  HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

  The page discusses tobacco and nicotine products generally and does not identify Nicotiana rustica botanically or distinguish it from Nicotiana tabacum.

• Nicotine ingestion may cause acute toxicosis in cats, but the page states that no established toxic threshold exists for cats.

  HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

  The page provides no cat-specific dose or threshold and does not botanically distinguish Nicotiana rustica from other tobacco sources.

• Environmental tobacco smoke exposure was associated with increased risk of malignant lymphoma in pet cats.

  MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

  The page names tobacco/environmental tobacco smoke but does not identify the tobacco species; this claim is mapped provisionally to strong tobacco.

• The page’s general toxicity-to-pets text describes tobacco (Nicotiana) poisoning as causing initial low heart and respiratory rates, followed by overstimulation, uncontrolled urination or defecation, tremors, seizures, paralysis, and death; it does not separately assign a toxicity designation to cats.

  MODERATE · poison_control_database · Tobacco Is Toxic To Dogs | Pet Poison Helpline®

  The clinical signs are presented in general pet text rather than separately attributed to cats; the page discusses Nicotiana generally and does not provide species-specific evidence for Nicotiana rustica.

• Nicotine ingestion can cause clinically important acute toxicosis in dogs; the page states that a dose of 9–12 mg/kg is considered lethal.

  HIGH · poison_control_database · Nicotine & Tobacco | American College of Veterinary Pharmacists

  The dose information concerns nicotine generally, not a botanically identified Nicotiana rustica product.

• A dog died from nicotine poisoning after eating an electronic cigarette capsule.

  HIGH · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

  The capsule was identified as causing nicotine poisoning, but the page does not identify the tobacco species or capsule composition beyond nicotine.

• Exposure to environmental tobacco smoke was associated with cancer of the nasal cavity and paranasal sinuses in pet dogs.

  MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

  The page names tobacco/environmental tobacco smoke but does not identify the tobacco species; this claim is mapped provisionally to strong tobacco.

• Nicotine ingestion is dangerous in dogs.

  HIGH · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

  The page names nicotine rather than a specific tobacco species or product.

• Passive exposure to environmental cigarette smoke was associated with airway limitation in dogs with chronic cough.

  MODERATE · regulatory_guidance · Be Smoke-free and Help Your Pets Live Longer, Healthier ...

  The page names tobacco/environmental cigarette smoke but does not identify the tobacco species; this claim is mapped provisionally to strong tobacco.

• The page states that tobacco (Nicotiana) is toxic to dogs. Nicotine and other pyridine and piperidine alkaloids may cause initial bradycardia and respiratory depression, followed by overstimulation, uncontrolled urination or defecation, tremors, seizures, paralysis, and death.

  HIGH · poison_control_database · Tobacco Is Toxic To Dogs | Pet Poison Helpline®

  The page discusses Nicotiana generally and does not provide species-specific evidence for Nicotiana rustica.