Sage

Research corpus coverage

Chemistry notes

• CHEMISTRY: Relevant reported constituents include thujone; camphor; rosmarinic acid; constituent presence alone does not establish clinical efficacy.

Traditional / historical use

Documented traditional use — not a claim of established efficacy.

• TRADITIONAL: Sage has been used for sore throat; sweating; digestive complaints; memory; this records historical/traditional use and does not establish efficacy.

  MODERATE · evidence synthesis/fact sheet · NCCIH Herbs at a Glance

Modern evidence

• EVIDENCE: For the major use set (sore throat; sweating; digestive complaints; memory), the evidence assessment is limited/mixed: Limited/preliminary human evidence; no condition clearly established.

  MODERATE · regulatory monograph and mixed scientific literature · NCCIH Herbs at a Glance

  Mixed findings, product heterogeneity, or indirect evidence are preserved in the detailed profile.

Forms used traditionally

A listed form does not imply it suits every plant part, or that one preparation is interchangeable with another — see the plant’s own notes below.

Cats & dogs

• High risk

  Sage essential oil is identified as an oil that can cause seizures in companion animals.

  Intrinsic toxicity · OTHER · sage essential oil · MODERATE · veterinary_manual · Toxicosis por aceites esenciales en animales - Toxicología

• High risk

  Sage oil is listed among essential oils that can cause seizures in animals.

  Intrinsic toxicity · INHALATION · sage essential oil · HIGH · veterinary_manual · Toxicoses From Essential Oils in Animals - Toxicology

• High risk

  Sage essential oil is listed among common essential oils that can cause poisoning in animals.

  Intrinsic toxicity · OTHER · essential oil · HIGH · poison_control_database · Essential Oils | Pet Poison Helpline®

Additional safety notes (general, unstructured)

Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.

• SAFETY: Major issues include High-thujone products and essential oil can cause seizures. Contraindications/cautions include Seizure disorders.

  HIGH · evidence synthesis/fact sheet · NCCIH Herbs at a Glance

• SAFETY: Clinically relevant interaction concerns include Potential interactions with anticonvulsants, sedatives and diabetes drugs.

  MODERATE · evidence synthesis/fact sheet · NCCIH Herbs at a Glance

  Some interactions are theoretical or based on case reports/pharmacokinetics rather than outcome trials.

• SAFETY: Pregnancy/lactation reference: Avoid high-dose or essential-oil use in pregnancy/lactation.

  MODERATE · regulatory monograph or evidence synthesis · NCCIH Herbs at a Glance

  Absence of evidence is not evidence of safety.

• Sage essential oil is identified as an oil that can cause seizures in companion animals.

  MODERATE · veterinary_manual · Toxicosis por aceites esenciales en animales - Toxicología

  The page names sage oil but does not specify Salvia officinalis or a toxic constituent.

• Sage oil is listed among essential oils that can cause seizures in animals.

  HIGH · veterinary_manual · Toxicoses From Essential Oils in Animals - Toxicology

• Sage essential oil is listed among common essential oils that can cause poisoning in animals.

  HIGH · poison_control_database · Essential Oils | Pet Poison Helpline®

  No sage-specific toxic constituent, dose, route-specific profile, or sign profile is provided.

Taxonomic identity note

• Sage is treated here as Salvia officinalis L. in the family Lamiaceae; recorded older names include Salvia minor Garsault.