Star anise
Illicium verum Hook.f.Schisandraceae // fruit
Overview
Plant parts
fruit
Known constituents
trans-anethole, shikimic acid
Research corpus coverage
Chemistry notes
- CHEMISTRY: Relevant reported constituents include trans-anethole; shikimic acid; constituent presence alone does not establish clinical efficacy.
Uses & Evidence
Traditional / historical use
Documented traditional use — not a claim of established efficacy.
TRADITIONAL: Star anise has been used for digestive and respiratory complaints; flavoring; this records historical/traditional use and does not establish efficacy.
MODERATE · regulatory monograph · WHO Monographs on Selected Medicinal Plants
Modern evidence
EVIDENCE: For the major use set (digestive and respiratory complaints; flavoring), the evidence assessment is insufficient: Insufficient clinical evidence for medicinal use.
LOW · regulatory monograph and mixed scientific literature · WHO Monographs on Selected Medicinal Plants
Preparation
Forms used traditionally
A listed form does not imply it suits every plant part, or that one preparation is interchangeable with another — see the plant’s own notes below.
PREPARATION: The medicinal material is fruit; traditional and modern forms include infusion/tea, tincture, powder/capsule, extract. No dose or potency is specified.
MODERATE · regulatory monograph · EMA European Union herbal monographs and list entries
Preparation-specific evidence should not be generalized across extracts, teas, oils, or whole herb.
Safety
Additional safety notes (general, unstructured)
Free-text safety notes carried from their source — not broken out by species, route, or hazard type, and not equivalent to the structured records above. Each note names the kind of source it came from.
SAFETY: Major issues include Substitution can cause seizures and severe toxicity; oil is concentrated. Contraindications/cautions include Infants; seizure disorders.
HIGH · observational/case series and expert review · LiverTox: Herbal and Dietary Supplements
SAFETY: Clinically relevant interaction concerns include No established major interactions; concentrated oil may add to neurotoxicity.
MODERATE · observational/case series and expert review · LiverTox: Herbal and Dietary Supplements
Some interactions are theoretical or based on case reports/pharmacokinetics rather than outcome trials.
SAFETY: Pregnancy/lactation reference: Food spice differs; medicinal use in pregnancy/lactation unsupported.
MODERATE · regulatory monograph or evidence synthesis · WHO Monographs on Selected Medicinal Plants
Absence of evidence is not evidence of safety.
Preparation × species risk matrix
Unknown means insufficient evidence was located — not that a form is safe.
Cats
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Dogs
- tinctureCaution
- concentrated extractUnknown
- essential oilUnknown
- glyceriteUnknown
- infused oilUnknown
- salveUnknown
- smoke/combustionUnknown
- tea/infusionUnknown
- whole herbUnknown
Identity
- Possible adulterantJapanese star anise
FDA warned that Chinese star anise may contain toxic Japanese star anise.
Why it matters: Contaminated tea was associated with seizures, vomiting, jitteriness, and abnormal eye movements, including illness in infants.
HIGH · Center for Food Safety and Applied Nutrition 2003
- Common-name collisionAnise
Anise and star anise share an anise flavor/common-name stem but are botanically unrelated.
MODERATE · GBIF taxonomic backbone and Apothecary corpus identity note
- Synonym
GBIF resolves Illicium san-ki Perr. as a synonym of Illicium verum. The older name still appears in herbal and taxonomic literature.
HIGH · GBIF Species Match API
Botanical synonym
Illicium san-ki Perr.
Taxonomic identity note
- Star anise is treated here as Illicium verum Hook.f. in the family Schisandraceae; recorded older names include Illicium san-ki Perr..
Sources
Research records are source-linked but may not yet be editorially reviewed.
WHO monograph
NIH LiverTox monograph
- Plants of the World Online1 claim
botanical taxonomy database
EMA monograph
- GBIF Species Match API1 claim
authoritative taxonomic database
government safety advisory
authoritative taxonomic database plus curated corpus note